HG C. difficile
Clostridium difficile (C. difficile), the major cause of hospital-acquired diarrhoea, is highly resistant to standard cleaning methods and can lead to dangerous outbreaks in healthcare facilities if undetected. Up to 25% of antibiotic-associated diarrhoea is caused by C. difficile infection. C. difficile outbreaks can be fatal, particularly in immune-compromised and elderly patients (≥ 20%).
Unmet Clinical Need:
- Accurate diagnosis
- Rapid results – Current culture methods can take up to 72 hrs
- Sensitivity across all toxigenic strains
The Hg Solution:
- 95.5% Sensitivity & 96.9% Specificity
- HG C. difficile gives results in ≤ 60 minutes.
- Detection across all toxigenic strains (A&B)
The HG C. difficile test enables highly sensitive and rapid diagnosis, allowing for timely and effective treatment and the prevention of outbreaks.
|Methodology:||Loop Mediated Isothermal Amplification (LAMP)|
|Target:||Toxigenic strains (A&B) of Clostridium difficile|
|Sample types:||Unformed stool|
|Hands-on time:||≤ 4 minutes|
|Sample to result:||≤ 60 minutes|
|Product Name||# of Tests||Catalogue|
|HG C. Difficile||30||HGCDIFFR|
|HG C. Difficile Control||18||HGCDIFFC|
*FDA submission is planned. Product is not available for sale in the US market.
1 J. Bartlett and D.Gerding, “Clinical recognition and diagnosis of Clostridium difficile infection,” Clinical Infectious Diseases, Vol. 46 (Suppl. 1), S12-S18, 2008.
2 J. Pépin, L. Valiquette and B. Cossette, “Mortality attributable to nosocomial Clostridium difficile–associated disease during an epidemic caused by a hypervirulent strain in Quebec,” Canadian Medical Association Journal, vol. 173, pp 1037-1042, 2005.